Article
Polymorphisms and haplotypes of the miR-148/152 family are associated with the risk and clinicopathological features of gastric cancer in a Northern Chinese population.
Mutagenesis - 1 Nov 2014
Chen Xiaowan, Wang Guoli, Lu Xiaoli, Gao Peng, Song Yongxi, Sun Jingxu, Li Ailin, Xu Yingying, Xu Huimian, Wang Zhenning
Abstract excerpt
Our previous studies showed that the expressions of miR-148a, miR-152 and miR-148b are altered in gastric cancer (GC). The present study aimed to find relationship between individual single nucleotide polymorphisms (SNPs) or haplotypes of these miRNAs and susceptibility, clinicopathological parameters and prognosis of GC in a large sample of the Han population of Northern China. Twelve SNPs were genotyped using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.