Article
The role of G protein coupled receptor-mediated signaling in the biological properties of Acanthamoeba castellanii of the T4 genotype.
Microbial pathogenesis - 1 Apr 2015
Aqeel Yousuf, Siddiqui Ruqaiyyah, Manan Zainab, Khan Naveed Ahmed
Abstract excerpt
Despite advances in antimicrobial chemotherapy and supportive care, the prognosis of Acanthamoeba infections remains poor, suggesting that new targets are needed that can affect parasite survival and host-pathogen interactions. G proteins and their coupled receptors are well known regulators of a variety of cellular functions. The overall aim of the present study was to study the role of G-protein coupled...
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