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Distinct immunomodulatory properties of extracellular vesicles released by different strains of Acanthamoeba.

Cell biology international - 1 May 2021

Costa Adriana Oliveira, Chagas Isabela Aurora Rodrigues, de Menezes-Neto Armando, Rêgo Felipe Dutra, Nogueira Paula Monalisa, Torrecilhas Ana Claudia, Furst Cinthia, Fux Blima, Soares Rodrigo Pedro

Abstract excerpt

Free living amoeba of the genus Acanthamoeba are opportunist protozoan involved in corneal, systemic, and encephalic infections in humans. Most of the mechanisms underlying intraspecies variations and pathogenicity are still unknown. Recently, the release of extracellular vesicles (EVs) by Acanthamoeba was reported. However, comparative characterization of EVs from distinct strains is not available. The aim of...

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PMID: 33448518
DOI: 10.1002/cbin.11551

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