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Lactase can target cellular differentiation of Acanthamoeba castellanii belonging to the T4 genotype.

Parasitology research - 31 Jan 2024

Simau Fathimath Afaaf, Ahmed Usman, Khan Khalid Mohammed, Khan Naveed Ahmed, Siddiqui Ruqaiyyah, Alharbi Ahmad M, Alfahemi Hasan, Anwar Ayaz

Abstract excerpt

The free living Acanthamoeba spp. are ubiquitous amoebae associated with potentially blinding disease known as Acanthamoeba keratitis (AK) and a fatal central nervous system infection granulomatous amoebic encephalitis (GAE). With the inherent ability of cellular differentiation, it can phenotypically transform to a dormant cyst form from an active trophozoite form. Acanthamoeba cysts are highly resistant to...

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PMID: 38294565
DOI: 10.1007/s00436-024-08131-2

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