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Sterol Biosynthesis Contributes to Brefeldin-A-Induced Endoplasmic Reticulum Stress Resistance in Chlamydomonas reinhardtii.

Plant & cell physiology - 27 Jun 2024

Je Sujeong, Choi Bae Young, Kim Eunbi, Kim Kyungyoon, Lee Yuree, Yamaoka Yasuyo

Abstract excerpt

The endoplasmic reticulum (ER) stress response is an evolutionarily conserved mechanism in most eukaryotes. In this response, sterols in the phospholipid bilayer play a crucial role in controlling membrane fluidity and homeostasis. Despite the significance of both the ER stress response and sterols in maintaining ER homeostasis, their relationship remains poorly explored. Our investigation focused on...

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PMID: 37864404
DOI: 10.1093/pcp/pcad131

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