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Article

Structure-based mutational analysis of several sites in the E protein: implications for understanding the entry mechanism of Japanese encephalitis virus.

Journal of virology - 1 May 2015

Liu Haibin, Liu Yi, Wang Shaobo, Zhang Yanjun, Zu Xiangyang, Zhou Zheng, Zhang Bo, Xiao Gengfu

Abstract excerpt

UNLABELLED: Japanese encephalitis virus (JEV), which causes viral encephalitis in humans, is a serious risk to global public health. The JEV envelope protein mediates the viral entry pathway, including receptor-binding and low-pH-triggered membrane fusion. Utilizing mutagenesis of a JEV infectious cDNA clone, mutations were introduced into the potential receptor-binding motif or into residues critical for...

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Identifiers

PMID: 25762738
DOI: 10.1128/JVI.00293-15
PMCID: PMC4442514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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