Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating polymorphisms in membrane-associated transporter protein SLC45A2, using sucrose transporters as a model.

Molecular medicine reports - 1 Jul 2015

Reinders Anke, Ward John M

Abstract excerpt

Solute carrier family 45 member 2 encodes the melanosomal membrane protein, membrane-associated transporter protein (MATP), of unknown function, that is required for normal melanin synthesis. The present study analyzed the effects of two human MATP mutations, D93N, which causes oculocutaneous albinism 4 (OCA4), and L374F, which is correlated with light pigmentation in European populations. Corresponding mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albinism, Oculocutaneous
Share to Antigens, Neoplasm
Share to Biological Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanins

Share to Membrane Transport Proteins

Share to Oocytes

Share to Sucrose

Share to Xenopus laevis

Source

Identifiers

PMID: 25760657
DOI: 10.3892/mmr.2015.3462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating polymorphisms in membrane-associated transporter protein SLC45A2, using sucrose transporters as a model.PMID 25760657Read ↗

Identification of two novel mutations in the SLC45A2 gene in a Hungarian pedigree affected by unusual OCA type 4.Semantic proximity Read ↗

Sugar transporter SLC45 gene family members: roles in malignant tumors and research progress.Semantic proximity Read ↗

Oculocutaneous albinism type 4: six novel mutations in the membrane‐associated transporter protein gene and their phenotypesSemantic proximity Read ↗

SLC45A2 variations in Indian oculocutaneous albinism patients.Semantic proximity Read ↗

Common dominant-negative spectrum of SLC45A2 mutations in OCA4 defined by endoplasmic reticulum retention.Semantic proximity Read ↗

Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci.Semantic proximity Read ↗

Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase Activity.Semantic proximity Read ↗

Promoter polymorphisms in the MATP (SLC45A2) gene are associated with normal human skin color variation.Semantic proximity Read ↗

Mutational Analysis on Membrane Associated Transporter Protein (MATP) and Their Structural Consequences in Oculocutaeous Albinism Type 4 (OCA4)-A Molecular Dynamics Approach.Semantic proximity Read ↗

SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.Semantic proximity Read ↗

Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease.Semantic proximity Read ↗

Impaired function of the tonoplast-localized sucrose transporter in rice, OsSUT2, limits the transport of vacuolar reserve sucrose and affects plant growth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.