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Article

Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci.

The Journal of investigative dermatology - 1 Feb 2009

Cook Anthony L, Chen Wei, Thurber Amy E, Smit Darren J, Smith Aaron G, Bladen Timothy G, Brown Darren L, Duffy David L, Pastorino Lorenza, Bianchi-Scarra Giovanna, Leonard J Helen, Stow Jennifer L, Sturm Richard A

Abstract excerpt

Single nucleotide polymorphisms (SNPs) within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P genes have been associated with natural variation of pigmentation traits in human populations. Here, we describe the characterization of human primary melanocytic cells genotyped for polymorphisms within the MATP, NCKX5, or OCA2 loci. On the basis of genotype, these cultured cells reflect the phenotypes observed by others in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18650849
DOI: 10.1038/jid.2008.211

Genes

OCA2
TYR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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