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Article

Ras moves to stay in place.

Trends in cell biology - 1 Apr 2015

Schmick Malte, Kraemer Astrid, Bastiaens Philippe I H

Abstract excerpt

Ras is a major intracellular signaling hub. This elevated position comes at a precarious cost: a single point mutation can cause aberrant signaling. The capacity of Ras for signaling is inextricably linked to its enrichment at the plasma membrane (PM). This PM localization is dynamically maintained by three essential elements: alteration of membrane affinities via lipidation and membrane-interaction motifs;...

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PMID: 25759176
DOI: 10.1016/j.tcb.2015.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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