Article
Association of folate metabolism gene polymorphisms and pulmonary embolism: A case-control study of West-Siberian population.
Thrombosis research - 1 May 2015
Karmadonova N A, Shilova A N, Kozyreva V S, Subbotovskaya A I, Klevanets J E, Karpenko A A
Abstract excerpt
INTRODUCTION: Our objective was to investigate the association between gene polymorphisms of folate cycle (MTHFR 677 C>T, MTHFR 1298 A>C, MTR 2756 A>G, and MTRR 66 A>G) and the risk of pulmonary embolism (PE) in a case-control study. MATERIALS AND METHODS: 177 PE patients (87 women and 90 men) were compared to a healthy control group (461 people, 123 women, 326 men). All of them are residents of Novosibirsk...
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