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Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

10 Mar 2015

Abstract excerpt

To understand neuroinflammation-related gene regulation during normal aging and in sporadic Alzheimer disease (sAD), we performed functional genomics analysis and analyzed messenger RNA (mRNA) expression by quantitative reverse transcription-polymerase chain reaction of 22 genes involved in neuroinflammation-like responses in the cerebral cortex of wild-type and APP/PS1 transgenic mice. For direct comparisons,...

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PMID: 25756590
DOI: 10.1097/nen.0000000000000176

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