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Article

Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.

Journal of cutaneous pathology - 1 May 2015

Stockman David L, Curry Jonathan L, Torres-Cabala Carlos A, Watson Ian R, Siroy Alan E, Bassett Roland L, Zou Lihua, Patel Keyur P, Luthra Rajyalakshmi, Davies Michael A, Wargo Jennifer A, Routbort Mark A, Broaddus Russell R, Prieto Victor G, Lazar Alexander J, Tetzlaff Michael T

Abstract excerpt

BACKGROUND: SMARCB1 (INI1/BAF47/SNF5) encodes a part of a multiprotein complex that regulates gene expression through chromatin remodeling. SMARCB1 expression is lost or downregulated in multiple human tumors, including epithelioid sarcoma, meningioma and rhabdoid tumors of the brain, soft tissue...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Source

Identifiers

PMID: 25754356
DOI: 10.1111/cup.12481

Genes

SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25754356-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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