Achromatopsia in three sibling Labrador Retrievers in the UK.

Abstract excerpt

Achromatopsia was identified in three Labrador Retriever littermates. The dogs demonstrated day blindness, negotiating obstacles under low-light conditions, but apparently blind when outdoors. One of the dogs presented with immature bilateral diffuse posterior cortical cataracts and clinical signs of day blindness became apparent following cataract extraction surgery. Electroretinography demonstrated an absence...

Topics

• Animals
• Color Vision Defects
• Cyclic Nucleotide-Gated Cation Channels
• Dog Diseases
• Dogs
• Female
• Gene Deletion
• Genetic Predisposition to Disease
• Male
• Mutation, Missense
• Pedigree
• United Kingdom