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Article

Visual system pathology in a canine model of CLN5 neuronal ceroid lipofuscinosis.

Experimental eye research - 1 Sept 2021

Kick Grace Robinson, Meiman Elizabeth J, Sabol Julianna C, Whiting Rebecca E H, Ota-Kuroki Juri, Castaner Leilani J, Jensen Cheryl A, Katz Martin L

Abstract excerpt

CLN5 neuronal ceroid lipofuscinosis is a hereditary neurodegenerative disease characterized by progressive neurological decline, vision loss and seizures. Visual impairment in children with CLN5 disease is attributed to a progressive decline in retinal function accompanied by retinal degeneration as well as impaired central nervous system function associated with global brain atrophy. We studied visual system...

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Identifiers

PMID: 34216614
DOI: 10.1016/j.exer.2021.108686
PMCID: PMC8429270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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