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Article

Detection of EGFR-TK domain-activating mutations in NSCLC with generic PCR-based methods.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Mar 2015

Shahi Rajendra B, De Brakeleer Sylvia, De Grève Jacques, Geers Caroline, In't Veld Peter, Teugels Erik

Abstract excerpt

Somatic mutations in the epidermal growth factor receptor-tyrosine kinase (EGFR-TK) domain of non-small cell lung cancer (NSCLC) influence the responsiveness of these tumors to EGFR-TK inhibitors, indicating their usefulness as a predictive molecular marker. However, for mutation analysis, the am...

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Source

Identifiers

PMID: 25751592
DOI: 10.1097/PDM.0000000000000035

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25751592-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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