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Article

The content of mutant EGFR DNA correlates with response to EGFR-TKIs in lung adenocarcinoma patients with common EGFR mutations.

Medicine - 1 Jun 2016

Hung Ming-Szu, Lung Jr-Hau, Lin Yu-Ching, Fang Yu-Hung, Hsieh Meng-Jer, Tsai Ying-Huang

Abstract excerpt

This study aimed to elucidate the association of the content of mutant epidermal growth factor receptor (EGFR) deoxyribonucleic acid (DNA) with the treatment response to EGFR-tyrosine kinase inhibitor (TKI) and survival in patients with lung cancer.This retrospective cohort study included 77 lung adenocarcinoma patients with common EGFR mutations from December 2012 to February 2015. The content of mutant EGFR DNA...

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Identifiers

PMID: 27368002
DOI: 10.1097/MD.0000000000003991
PMCID: PMC4937916

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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