Fibrinogen alpha amyloidosis: insights from proteomics

Abstract excerpt

Introduction: Systemic amyloidosis is a diverse group of diseases that, although rare, pose a serious health issue and can lead to organ failure and death. Amyloid typing is essential in determining the causative protein and initiating proper treatment. Mass spectrometry-based proteomics is currently the most sensitive and accurate means of typing amyloid.Areas covered: Amyloidosis can be systemic or localized,...

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