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Quantitative assessment of telomerase components in cancer cell lines

4 Mar 2015

Abstract excerpt

Besides its canonical function of catalyzing the formation of telomeric repeats, many groups have recently reported non-canonical functions of hTERT in particular, and telomerase in general. Regulating transcription is the central basis of non-canonical functions of telomerase. However, unlike reverse transcriptase activity of telomerase that requires only a few molecules of enzymatically active hTERT,...

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PMID: 25749370
DOI: 10.1016/j.febslet.2015.02.035

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