Article
Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress
14 Oct 2014
Abstract excerpt
Telomerase activity is essential for human cancer cells in order to maintain telomeres and provide unlimited proliferation potential and cellular immortality. However, additional non-telomeric roles emerge for the telomerase protein TERT that can impact tumourigenesis and cancer cell properties. This review summarises our current knowledge of non-telomeric functions of telomerase in human cells, with a special...
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