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Article

Human telomerase activity regulation

17 Nov 2010

Abstract excerpt

Telomerase has been recognized as a relevant factor distinguishing cancer cells from normal cells. Thus, it has become a very promising target for anticancer therapy. The cell proliferative potential can be limited by replication end problem, due to telomeres shortening, which is overcome in cancer cells by telomerase activity or by alternative telomeres lengthening (ALT) mechanism. However, this multisubunit...

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Share to Telomeres, Telomerase, and Senescence
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PMID: 21086176
DOI: 10.1007/s11033-010-0439-x

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