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Article

Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation

6 Mar 2015

Abstract excerpt

Increasing evidence shows that microRNAs play an important role in kidney disease. However, functions of long noncoding RNAs (lncRNAs) in kidney diseases remain undefined. We have previously shown that TGF-β1 plays a diverse role in renal inflammation and fibrosis and Smad3 is a key mediator in this process. In this study, we used RNA-sequencing to identify lncRNAs related to renal inflammation and fibrosis in...

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PMID: 25743111
DOI: 10.1038/mt.2015.31

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