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Article

The tail domain is essential but the head domain dispensable for C. elegans intermediate filament IFA-2 function.

PloS one - 1 Jan 2015

Williams Kyle, Williams Kristen, Baucher Hallie M, Plenefisch John

Abstract excerpt

The intermediate filament protein IFA-2 is essential for the structural integrity of the Caenorhabditis elegans epidermis. It is one of the major components of the fibrous organelle, an epidermal structure comprised of apical and basal hemidesmosomes linked by cytoplasmic intermediate filaments that serve to transmit force from the muscle to the cuticle. Mutations of IFA-2 result in epidermal fragility and...

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Identifiers

PMID: 25742641
DOI: 10.1371/journal.pone.0119282
PMCID: PMC4351089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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