Article
The Caenorhabditis elegans vab-10 spectraplakin isoforms protect the epidermis against internal and external forces.
The Journal of cell biology - 26 May 2003
Bosher Julia M, Hahn Bum-Soo, Legouis Renaud, Sookhareea Satis, Weimer Robby M, Gansmuller Anne, Chisholm Andrew D, Rose Ann M, Bessereau Jean-Louis, Labouesse Michel
Abstract excerpt
Morphogenesis of the Caenorhabditis elegans embryo is driven by actin microfilaments in the epidermis and by sarcomeres in body wall muscles. Both tissues are mechanically coupled, most likely through specialized attachment structures called fibrous organelles (FOs) that connect muscles to the cuticle across the epidermis. Here, we report the identification of new mutations in a gene known as vab-10, which lead...
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