Article
Death following traumatic brain injury in Drosophila is associated with intestinal barrier dysfunction.
eLife - 5 Mar 2015
Katzenberger Rebeccah J, Chtarbanova Stanislava, Rimkus Stacey A, Fischer Julie A, Kaur Gulpreet, Seppala Jocelyn M, Swanson Laura C, Zajac Jocelyn E, Ganetzky Barry, Wassarman David A
Abstract excerpt
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Unfavorable TBI outcomes result from primary mechanical injuries to the brain and ensuing secondary non-mechanical injuries that are not limited to the brain. Our genome-wide association study of Drosophila melanogaster revealed that the probability of death following TBI is associated with single nucleotide polymorphisms in genes...
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