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Article

Genetic variation in innate immune gene expression influences mortality after traumatic brain injury in Drosophila.

G3 (Bethesda, Md.) - 6 May 2026

Katzenberger Rebeccah J, Sharp Nathaniel P, Ganetzky Barry, Wassarman David A

Abstract excerpt

Traumatic brain injury (TBI) is a leading cause of disability and death, with outcome severity varying widely even among individuals with comparable injuries. A major challenge is to identify pathways that underlie this variation and could be targeted to improve therapies. Innate immune pathways are candidates because they are rapidly activated after TBI and contribute to neurodegenerative disorders. Using a...

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Identifiers

PMID: 41823481
DOI: 10.1093/g3journal/jkag060
PMCID: PMC13148387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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