Article

Glial immune-related pathways as mediators of closed head TBI effects on behavior in <i>Drosophila</i>

2018-09-20

Abstract excerpt

In traumatic brain injury (TBI) the initial injury phase is followed by a secondary phase that contributes to neurodegeneration. Yet the mechanisms leading to neuropathology in vivo remain to be elucidated. To address this question, we developed a Drosophila head-specific model for TBI, which we term Drosophila Closed Head Injury (dCHI), where well-controlled, non-penetrating strikes are directly delivered to the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2b8d0d38-5f85-57bb-adbc-b8bd01f5c1ad
DOI: 10.1101/422535

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Glial immune-related pathways as mediators of closed head TBI effects on behavior in <i>Drosophila</i>DOI 10.1101/422535Read

Glial immune-related pathways mediate effects of closed head traumatic brain injury on behavior and lethality in Drosophila.Semantic proximity Read

Mammalian Models of Traumatic Brain Injury and a Place for Drosophila in TBI ResearchSemantic proximity Read

i Drosophila i models of traumatic brain injurySemantic proximity Read

A <i>Drosophila</i> model of closed head traumatic brain injurySemantic proximity Read

Dynamic neural and glial responses of a head-specific model for traumatic brain injury in DrosophilaSemantic proximity Read

Age and Diet Affect Genetically Separable Secondary Injuries that Cause Acute Mortality Following Traumatic Brain Injury in Drosophila.Semantic proximity Read

Modeling Sex Differences and Neurodegeneration in Repetitive Traumatic Brain Injury Using <i>Drosophila</i>Semantic proximity Read

Dietary restriction ameliorates TBI-induced phenotypes in Drosophila melanogaster.Semantic proximity Read

Survival Following Traumatic Brain Injury in Drosophila Is Increased by Heterozygosity for a Mutation of the NF-κB Innate Immune Response Transcription Factor Relish.Semantic proximity Read

A Method to Inflict Closed Head Traumatic Brain Injury in DrosophilaSemantic proximity Read

dTBI: A paradigm for closed-head injury in DrosophilaSemantic proximity Read

Drosophila melanogaster as a model to study age and sex differences in brain injury and neurodegeneration after mild head traumaSemantic proximity Read