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Article

Survival Following Traumatic Brain Injury in Drosophila Is Increased by Heterozygosity for a Mutation of the NF-κB Innate Immune Response Transcription Factor Relish.

Genetics - 1 Dec 2020

Swanson Laura C, Trujillo Edna A, Thiede Gene H, Katzenberger Rebeccah J, Shishkova Evgenia, Coon Joshua J, Ganetzky Barry, Wassarman David A

Abstract excerpt

Traumatic brain injury (TBI) pathologies are caused by primary and secondary injuries. Primary injuries result from physical damage to the brain, and secondary injuries arise from cellular responses to primary injuries. A characteristic cellular response is sustained activation of inflammatory pathways commonly mediated by nuclear factor-κB (NF-κB) transcription factors. Using a Drosophila melanogaster TBI model,...

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Source

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Identifiers

PMID: 33109529
DOI: 10.1534/genetics.120.303776
PMCID: PMC7768241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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