Article
Mitochondrial dysfunction and risk of cancer.
British journal of cancer - 17 Mar 2015
Lund M, Melbye M, Diaz L J, Duno M, Wohlfahrt J, Vissing J
Abstract excerpt
BACKGROUND: Mitochondrial mutations are commonly reported in tumours, but it is unclear whether impaired mitochondrial function per se is a cause or consequence of cancer. To elucidate this, we examined the risk of cancer in a nationwide cohort of patients with mitochondrial dysfunction. METHODS: We used nationwide results on genetic testing for mitochondrial disease and the Danish Civil Registration System, to...
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