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Article

Polymorphisms in microRNA target sites of forkhead box O genes are associated with hepatocellular carcinoma.

PloS one - 1 Jan 2015

Tan Chao, Liu Shun, Tan Shengkui, Zeng Xiaoyun, Yu Hongping, Li Anhua, Bei Chunhua, Qiu Xiaoqiang

Abstract excerpt

The forkhead box O (FOXO) transcription factors play important roles in various cancer development including Hepatocellular Carcinoma (HCC). In this study we conducted a hospital-based case control study including 1049 cases (HCC patients) and 1052 controls (non-tumor patients) to examine whether single nucleotide polymorphisms (SNPs) within microRNA (miRNA) target sites of FOXO genes confer HCC susceptibility. A...

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Topics

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Forkhead Transcription Factors

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Source

Open in PubMed Open full text

Identifiers

PMID: 25739100
DOI: 10.1371/journal.pone.0119210
PMCID: PMC4357486

Genes

FOXO1
FOXO3
FOXO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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