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Computational analysis of the LRRK2 interactome

19 Feb 2015

Abstract excerpt

LRRK2 was identified in 2004 as the causative protein product of the Parkinson's disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson's disease, alongside one associated with cancer. It is now well established that coding changes in LRRK2 are one of the most common causes of Parkinson's. Genome-wide association studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25737818
DOI: 10.7717/peerj.778

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