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Article

Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis.

European journal of human genetics : EJHG - 1 Nov 2015

de Leeuw Christiaan, Goudriaan Andrea, Smit August B, Yu Dongmei, Mathews Carol A, Scharf Jeremiah M, Verheijen Mark H G, Posthuma Danielle

Abstract excerpt

Tourette syndrome is a heritable neurodevelopmental disorder whose pathophysiology remains unknown. Recent genome-wide association studies suggest that it is a polygenic disorder influenced by many genes of small effect. We tested whether these genes cluster in cellular function by applying gene-set analysis using expert curated sets of brain-expressed genes in the current largest available Tourette syndrome...

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Identifiers

PMID: 25735483
DOI: 10.1038/ejhg.2015.22
PMCID: PMC4613465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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