Article
New amino acid changes in drug resistance sites and HBsAg in hepatitis B virus genotype H.
Journal of medical virology - 1 Jun 2015
Fernández-Galindo D A, Sánchez-Ávila F, Bobadilla-Morales L, Gómez-Quiróz P, Bueno-Topete M, Armendáriz-Borunda J, Sánchez-Orozco L V
Abstract excerpt
Long-term treatment with retrotranscriptase (RT) inhibitors eventually leads to the development of drug resistance. Drug-related mutations occur naturally and these can be found in hepatitis B virus (HBV) carriers who have never received antiviral therapy. HBsAg are overlapped with RT domain, thus nucleot(s)ide analogues (NAs) resistance mutations and naturally-occurring mutations can cause amino acid changes in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
