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Article

The tetrameric pheromone module SteC-MkkB-MpkB-SteD regulates asexual sporulation, sclerotia formation and aflatoxin production in Aspergillus flavus.

Cellular microbiology - 1 Jun 2020

Frawley Dean, Greco Claudio, Oakley Berl, Alhussain Mohamed M, Fleming Alastair B, Keller Nancy P, Bayram Özgür

Abstract excerpt

For eukaryotes like fungi to regulate biological responses to environmental stimuli, various signalling cascades are utilized, like the highly conserved mitogen-activated protein kinase (MAPK) pathways. In the model fungus Aspergillus nidulans, a MAPK pathway known as the pheromone module regulates development and the production of secondary metabolites (SMs). This pathway consists five proteins, the three...

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Identifiers

PMID: 32068947
DOI: 10.1111/cmi.13192
PMCID: PMC7202998

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