Article
Dynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress in Aspergillus nidulans.
Molecular & cellular proteomics : MCP - 1 Aug 2020
Chelius Cynthia, Huso Walker, Reese Samantha, Doan Alexander, Lincoln Stephen, Lawson Kelsi, Tran Bao, Purohit Raj, Glaros Trevor, Srivastava Ranjan, Harris Steven D, Marten Mark R
Abstract excerpt
The fungal cell-wall integrity signaling (CWIS) pathway regulates cellular response to environmental stress to enable wall repair and resumption of normal growth. This complex, interconnected, pathway has been only partially characterized in filamentous fungi. To better understand the dynamic cellular response to wall perturbation, a β-glucan synthase inhibitor (micafungin) was added to a growing A. nidulans...
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