Article
Role of GSTM1 (Present/Null) and GSTP1 (Ile105Val) polymorphisms in susceptibility to acute lymphoblastic leukemia among the South Indian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Suneetha K J, Nancy K Nirmala, Rajalekshmy K R, Sagar T G, Rajkumar T
Abstract excerpt
Acute lymphoblastic leukaemia (ALL) is the most common pediatric malignancy worldwide. The origin of this disease may be explained by a combination of genetic and environmental factors. Glutathione-s-transferases are a multi-gene family of enzymes involved in the detoxification of a wide variety of environmental carcinogens. A total of 92 immunophenotyped cases (below 25 years of age) and 150 cord blood controls...
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