MicroRNA biogenesis and cellular proliferation.

doi:10.1016/j.trsl.2015.01.012

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Article

MicroRNA biogenesis and cellular proliferation.

Translational research : the journal of laboratory and clinical medicine - 1 Aug 2015

Lenkala Divya, Gamazon Eric R, LaCroix Bonnie, Im Hae Kyung, Huang R Stephanie

Abstract excerpt

Given the fundamental roles of microRNAs (miRNAs) in physiological, developmental, and pathologic processes, we hypothesized that genes involved in miRNA biogenesis contribute to human complex traits. For 13 such genes, we evaluated the relationship between transcription and 2 classes of complex traits, namely cellular growth and sensitivity to various chemotherapeutic agents in a set of lymphoblastoid cell...

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Identifiers

PMID: 25724890
DOI: 10.1016/j.trsl.2015.01.012
PMCID: PMC4509805

Genes

AGO2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.