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Article

Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase.

Nucleic acids research - 11 Mar 2015

Tian Qingnan, Wang Caiyan, Liu Yuhuan, Xie Wei

Abstract excerpt

Aminoacyl-tRNA synthetases (aaRSs) play a crucial role in protein translation by linking tRNAs with cognate amino acids. Among all the tRNAs, only tRNA(His) bears a guanine base at position -1 (G-1), and it serves as a major recognition element for histidyl-tRNA synthetase (HisRS). Despite strong interests in the histidylation mechanism, the tRNA recognition and aminoacylation details are not fully understood. We...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25722375
DOI: 10.1093/nar/gkv129
PMCID: PMC4357726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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