Article
Distribution of HbS, HbC variants, ABO blood groups in relation to malaria infection among Saudi children in Jazan region.
Acta tropica - 1 Dec 2025
Qahtani Sultan A Al, Saleh Nada M, Alsubaie Razan S, Almutairi Raghad, Hamid Osama, Elhassan Lamyaa Am, Abushouk Amir, Ahmed Mohammed Seed, Nasr Amre
Abstract excerpt
Plasmodium falciparum remains a major public health challenge in the Jazan region, Saudi Arabia. This study investigated the influence of haemoglobin variants and ABO blood groups on malaria susceptibility, severity, and immune response among Saudi children. A total of 587 children were classified into malaria-free controls (MFC, n = 196), uncomplicated malaria (UM, n = 215), and severe malaria (SM, n = 176)....
Topics
- Saudi Arabia
- Malaria, Falciparum
- ABO Blood-Group System
- Disease Susceptibility
- Hemoglobin, Sickle
- Hemoglobin C
- Alleles
- Severity of Illness Index
- Plasmodium falciparum
- Antibodies, Protozoan
- Immunoglobulin G
- Case-Control Studies