Article
Type 2 Endometrial Cancer is Associated With a High Density of Tumor-Associated Macrophages in the Stromal Compartment.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Aug 2015
Kelly Michael G, Francisco Antonio M C, Cimic Adela, Wofford Anne, Fitzgerald Nora C, Yu Jie, Taylor Robert N
Abstract excerpt
INTRODUCTION: Tumor-associated macrophages (TAMs) play a pivotal role in orchestrating the microenvironment. The TAMs differentially polarize into M1 or M2 macrophages with distinct actions. The aim of our work is to characterize density, subtype, and location of TAMs in endometrial hyperplasia and cancer. METHODS: Formalin-fixed, paraffin-embedded sections of hyperplasia (n = 5), type 1 (n = 5), and type 2 (n =...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
