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Article

Detection of minimal residual disease in pediatric acute lymphoblastic leukemia

12 Jun 2013

Abstract excerpt

Minimal residual disease (MRD) is a powerful predictor of the overall response to treatment in childhood acute lymphoblastic leukemia (ALL). The most reliable and validated methods to assess MRD in ALL are flow cytometric (FCM) analysis of leukemia-associated immunophenotypes and polymerase chain reaction (PCR) amplification of antigen-receptor gene rearrangements. Results of studies correlating MRD with clinical...

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PMID: 23757107
DOI: 10.1002/cyto.b.21101

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