Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell multiomics reveals multiple adipogenic pathways and diverse multilineage specializations during embryonic fat tail morphogenesis

3 Sept 2025

Abstract excerpt

emerging as a critical regulator through its interaction with PPARG. Additionally, we delineated developmental trajectories and unique eGRNs underlying angiogenesis, osteogenesis, chondrogenesis, and myogenesis associated with fat formation. Our findings provide novel insights into embryonic adipogenesis in mammals and reveal critical regulons governing lineage specialization.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Lipid metabolism and biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 41019374
DOI: 10.1016/j.isci.2025.113496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell multiomics reveals multiple adipogenic pathways and diverse multilineage specializations during embryonic fat tail morphogenesisPMID 41019374Read ↗

Single cell transcriptomics identifies a unique adipocyte population that regulates bone marrow environmentSemantic proximity Read ↗

Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analysesSemantic proximity Read ↗

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environmentSemantic proximity Read ↗

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory networkSemantic proximity Read ↗

BMPER is a marker of adipose progenitors and adipocytes and a positive modulator of adipogenesisSemantic proximity Read ↗

Dissecting human skeletal stem cell ontogeny by single-cell transcriptomic and functional analysesSemantic proximity Read ↗

Adipogenesis: A Complex Interplay of Multiple Molecular Determinants and PathwaysSemantic proximity Read ↗

Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose HomeostasisSemantic proximity Read ↗

Comparative single-cell lineage tracing identifies distinct adipocyte precursor dynamics in skin and inguinal fatSemantic proximity Read ↗

Transcriptional and Epigenomic Regulation of AdipogenesisSemantic proximity Read ↗

Spatial transcriptomics maps distinct signatures of human intermuscular adipose expansion in miceSemantic proximity Read ↗

Extensive enhancer crosstalk controls PPARG2 activation during adipogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.