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Article

Systematic review and meta-analysis of Japanese familial Alzheimer's disease and FTDP-17.

Journal of human genetics - 1 May 2015

Kasuga Kensaku, Kikuchi Masataka, Tokutake Takayoshi, Nakaya Akihiro, Tezuka Toshiyuki, Tsukie Tamao, Hara Norikazu, Miyashita Akinori, Kuwano Ryozo, Ikeuchi Takeshi

Abstract excerpt

Mutations in APP, PSEN1 and PSEN2 as the genetic causes of familial Alzheimer's disease (FAD) have been found in various ethnic populations. A substantial number of FAD pedigrees with mutations have been reported in the Japanese population; however, it remains unclear whether the genetic and clinical features of FAD in the Japanese population differ from those in other populations. To address this issue, we...

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Source

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Identifiers

PMID: 25694106
DOI: 10.1038/jhg.2015.15
PMCID: PMC4521293

Genes

APP
PSEN1
MAPT
PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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