Article
MBL2 polymorphisms in women with atypical squamous cells of undetermined significance.
Journal of medical virology - 1 May 2015
Zupin Luisa, Polesello Vania, Casalicchio Giorgia, Freato Nadia, Maestri Iva, Comar Manola, Crovella Sergio, Segat Ludovica
Abstract excerpt
Infection with high risk Human papillomavirus (HPV) is the main known cause of cervical cancer. HPV induces different grades of lesions: among them, Atypical squamous cells of undetermined significance are abnormal lesions that could evolve in pre-cancer lesions or spontaneously regress. The mannose binding lectin (MBL) is an innate immunity serum protein also found in cervico-vaginal mucosa, whose expression is...
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