Article
MBL2 genetic screening in patients with recurrent vaginal infections.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Feb 2008
Milanese Michele, Segat Ludovica, De Seta Francesco, Pirulli Doroti, Fabris Annalisa, Morgutti Marcello, Crovella Sergio
Abstract excerpt
PROBLEM: Mannose-binding lectin (MBL) is an important component of the innate immunity, present at the mucosal level in vagina: a common pathogen's entry point. METHOD OF STUDY: We used a rapid genotyping method based on melting temperature assay to search for three single nucleotide polymorphisms (SNPs) located in the first exon of the MBL2 gene and we also measured MBL serum levels in patients with recurrent...
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