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Article

Intratumor heterogeneity and clonal evolution in an aggressive papillary thyroid cancer and matched metastases.

Endocrine-related cancer - 1 Apr 2015

Le Pennec Soazig, Konopka Tomasz, Gacquer David, Fimereli Danai, Tarabichi Maxime, Tomás Gil, Savagner Frédérique, Decaussin-Petrucci Myriam, Trésallet Christophe, Andry Guy, Larsimont Denis, Detours Vincent, Maenhaut Carine

Abstract excerpt

The contribution of intratumor heterogeneity to thyroid metastatic cancers is still unknown. The clonal relationships between the primary thyroid tumors and lymph nodes (LN) or distant metastases are also poorly understood. The objective of this study was to determine the phylogenetic relationships between matched primary thyroid tumors and metastases. We searched for non-synonymous single-nucleotide variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 19

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Source

Identifiers

PMID: 25691441
DOI: 10.1530/ERC-14-0351

Genes

KAZN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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