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Article

Role of tumor necrosis factor-alpha -238 G>A promoter region polymorphism on recurrent miscarriage: An association study and meta-analysis.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Oct 2023

Sudhir Neha, Kaur Mandeep, Singh Sukhjashanpreet, Beri Archana, Kaur Tajinder, Badaruddoza, Kaur Anupam

Abstract excerpt

BACKGROUND: Recurrent miscarriage (RM) is defined as the loss of two or more consecutive pregnancies. A functional SNP, -238G>A in the promoter region of TNF-α, affects the gene transcription activity with implications on human pregnancy. Previous limited studies, linking the TNF-α -238 G>A to the risk of recurrent miscarriage have been inconclusive. MATERIAL AND METHOD: The PCR-RLFP technique was used to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37766403
DOI: 10.1111/aji.13775

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TNF

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