Article
Association of IL-17A and IL-17 F gene polymorphisms with recurrent pregnancy loss in Iranian women.
Journal of assisted reproduction and genetics - 1 Nov 2014
Najafi Soheil, Hadinedoushan Hossein, Eslami Gilda, Aflatoonian Abbas
Abstract excerpt
PURPOSE: Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more miscarriages before the 20th week of pregnancy. T helper17 cells are a novel subset of T cells, which secrete IL (Interleukin)-17 and are known to be involved in inflammation, autoimmunity and rejection of non-self tissues. Herein, we studied the association between IL-17A rs2275913 and IL-17F rs763780 gene polymorphisms with RPL...
Topics
- Abortion, Habitual
- Adult
- Case-Control Studies
- Female
- Genetic Association Studies
- Genotype
