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Somatic calreticulin mutations in patients with Budd-Chiari syndrome and portal vein thrombosis

14 Feb 2015

Abstract excerpt

We studied the role of the recently identified CALR mutations in 141 patients with Budd-Chiari Syndrome (BCS) or portal vein thrombosis (PVT) in a large multinational cohort. A CALR mutation was present in one of the 141 patients (0.7%). This patient was previously diagnosed with primary myelofibrosis. This results in CALR positivity in one out of 44 (2.3%) patients with myeloproliferative neoplasm (MPN), and in...

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PMID: 25682604
DOI: 10.3324/haematol.2014.120857

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