Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic factors associated with exercise performance in atmospheric hypoxia.

Sports medicine (Auckland, N.Z.) - 1 May 2015

Hennis Philip J, O'Doherty Alasdair F, Levett Denny Z H, Grocott Michael P W, Montgomery Hugh M

Abstract excerpt

BACKGROUND AND OBJECTIVE: 'Natural selection' has been shown to have enriched the genomes of high-altitude native populations with genetic variants of advantage in this hostile hypoxic environment. In lowlanders who ascend to altitude, genetic factors may also contribute to the substantial interindividual variation in exercise performance noted at altitude. We performed a systematic literature review to identify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinin
Share to Altitude Sickness
Share to AMP Deaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Athletic Performance

Share to Exercise

Share to INDEL Mutation

Share to Oxygen Consumption

Share to Peptidyl-Dipeptidase A

Source

Open in PubMed Open full text

Identifiers

PMID: 25682119
DOI: 10.1007/s40279-015-0309-8
PMCID: PMC4544548

Genes

ACE
ADRB2
AMPD1

Variants

rs17602729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic factors associated with exercise performance in atmospheric hypoxia.PMID 25682119Read ↗

Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population.Semantic proximity Read ↗

A genetic predisposition score associates with reduced aerobic capacity in response to acute normobaric hypoxia in lowlanders.Semantic proximity Read ↗

Performance enhancing genetic variants, oxygen uptake, heart rate, blood pressure and body mass index of elite high altitude mountaineers.Semantic proximity Read ↗

The genetics of altitude tolerance: the evidence for inherited susceptibility to acute mountain sickness.Semantic proximity Read ↗

Evidence for and Against Genetic Predispositions to Acute and Chronic Altitude Illnesses.Semantic proximity Read ↗

Physiological Genomics of Adaptation to High-Altitude Hypoxia.Semantic proximity Read ↗

Evidence for a genetic basis for altitude-related illness.Semantic proximity Read ↗

Seq-ing Higher Ground: Functional Investigation of Adaptive Variation Associated With High-Altitude AdaptationSemantic proximity Read ↗

High-impact Genetic Variants in EGLN1, EPAS1, and Other Genes Identified in Mountaineers by Exome Sequencing.Semantic proximity Read ↗

Human genetic adaptation to high altitudes: Current status and future prospectsSemantic proximity Read ↗

Evidence for a genetic basis for altitude illness: 2010 update.Semantic proximity Read ↗

DNA Methylation Changes and Phenotypic Adaptations Induced Repeated Extreme Altitude Exposure at 8848 Meters.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.