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Article

Blood type gene locus has no influence on ACE association with Alzheimer's disease.

Neurobiology of aging - 1 Apr 2015

Braae Anne, Medway Christopher, Carrasquillo Minerva, Younkin Steven, Kehoe Patrick G, Morgan Kevin

Abstract excerpt

The ABO blood group locus was recently found to contribute independently and via interactions with angiotensin-converting enzyme (ACE) gene variation to plasma levels of ACE. Variation in ACE has previously been not only implicated as individually conferring susceptibility for Alzheimer's disease...

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Source

Identifiers

PMID: 25681990
DOI: 10.1016/j.neurobiolaging.2015.01.013

Genes

ACE
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25681990-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Blood type gene locus has no influence on ACE association with Alzheimer's disease.PMID 25681990Read ↗

Haplotypes extending across ACE are associated with Alzheimer's disease.Semantic proximity Read ↗

Quantitative variation in plasma angiotensin-I converting enzyme activity shows allelic heterogeneity in the ABO blood group locus.Semantic proximity Read ↗

A common variant of the ABO gene protects against hypertension in a Spanish population.Semantic proximity Read ↗

ACE I/D polymorphism is a risk factor of Alzheimer's disease but not of vascular dementiaSemantic proximity Read ↗

Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G protein beta3, either independently or interactively with apolipoprotein E.Semantic proximity Read ↗

Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes.Semantic proximity Read ↗

No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.Semantic proximity Read ↗

The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease.Semantic proximity Read ↗

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